1 | Fan Zhang, Yiying Wang, Yu Liu, Hao Han, Dandan Zhang, Xizhenzi Fan, Xiaona Du, Nikita Gamper, Hailin Zhang. Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF-induced pain. The Journal of Neuroscience, 2019. (IF 6.07) |
2 | Fan Zhang, Yani Liu, Feng Tang, Bo Liang, Huanming Chen, Hailin Zhang, Kewei Wang. Electrophysiological and pharmacological characterization of a novel and potent neuronal Kv7 channel opener SCR2682 for anti-epilepsy. The FASEB Journal, 2019. (IF 5.59) |
3 | Fan Zhang, Sylvain Gigout, Yu Liu, Yiying Wang, Han Hao, Noel J. Buckley, Hailin Zhang, Ian C. Wood, Nikita Gamper. Repressor element 1-silencing transcription factor drives the development of chronic pain states. Pain, 2019. (IF 6.03) |
4 | Fan Zhang, Yi Mi, Jinlong Qi, Junwei Li, Man Si, Bingcai Guan, Xiaona Guan, Hailong An, Hailin Zhang. Modulation of Kv7 potassium channels by a novel opener pyrazolo[1,5-a]pyrimidin-7(4H)-one compound QO-58. Br J Pharmacol, 168, 1030-1042, 2013. (IF 6.8) |
5 | Fan Zhang, Yani Liu, Dandan Zhang, Xizhenzi Fan, Decheng Shao, Han Li. Suppression of KCNQ/M potassium channel in dorsal root ganglia neurons contributes to the development of osteoarthritic pain. Pharmacology 2019. （IF 1.67） |
6 | Fan Zhang, Yanxin Cheng, Hong Li, Qingzhong Jia, Hailin Zhang, Senming Zhao. Inhibition of Kv7/M channel currents by the local anesthetic chloroprocaine. Pharmacology, 2015, 96, 124-130. （IF 1.67） |
7 | Jinlong Qi, Fan Zhang＃(Co-first author), Yi Mi, Yan Fu, Wen Xu, Diqun Zhang, Yibing Wu, Xiaona Du, Qingzhong Jia, Kewei Wang, Hailin Zhang. Design, synthesis and biological activity of pyrazolo[1,5-a]pyrimidin -7(4H)-ones as novel Kv7/KCNQ potassium channel activators. European Journal of Medicinal Chemistry, 2011, 46(3), 934-943. ( IF:3.3) |
8 | Rong Chen, Fan Zhang, Li Song, Yanan Shu, Yanling Lin, Lihua Dong, Xi Nie, Dandan Zhang, Peng Chen, Mei Han. Transcriptome profiling reveals that the SM22α-regulated molecular pathways contribute to vascular pathology. J Mol Cell Cardiol. 2014 Jul;72:263-72. （IF 5.1） |
9 | Yanan Shu, Fan Zhang, Wei Bi, Lihua Dong, Suibing Miao, Lili Zhao, Hong Wang, Mei Han. SM22α inhibits vascular inflammation via stabilization of IκBα in vascular smooth muscle cells. J Mol Cell Cardiol，2015, 7(84):191-9.（IF 4.65） |
10 | Lili Zhao, Fan Zhang, Peng Chen, Xiaoli Xie, Yongqing Dou, Yanan Shu, Mei Han. Insulin-independent GLUT4 translocation in proliferative vascular smooth muscle cells involves SM22α. J Mol Med, 2016.（IF 4.9） |
张凡，女，汉族，中共党员。博士，副教授，博士生导师。目前在创新药物研究及评价中心组建课题组，主要研究方向为离子通道功能调控在神经精神类疾病（如疼痛、癫痫、抑郁症等）中作用及作用机制，以离子通道为靶点的天然活性产物筛选、作用机制研究以及成药性评价。在Journal of Neuroscience, 等国内外杂志公开发表学术论文25余篇，参与获得国家授权专利1项，美国专利1项，荣获河北省优秀博士论文。主持国家自然科学基金面上项目、国家自然科学青年基金、河北省优秀青年基金、中国博士后基金面上项目一等资助、河北省自然科学基金及河北省教育厅优秀青年基金等项目, 参与国家基金委重大研究计划集成项目一项。指导大学生荣获2017年河北省创新创业年会特等奖；河北省“三三三”工程第三层次人才；河北省第三批青年拔尖人才。担任河北省数理医学青年委员会常务委员；担任北京神经科学学会青年委员会委员；担任河北省神经科学学会理事。